STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (294 aa)    
Predicted Functional Partners:
KRK94520.1
Homoserine dehydrogenase.
 
 0.999
KRK95513.1
Cystathionine gamma-synthase.
  
 
 0.967
metAA
Homoserine o-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
    
 0.961
KRK94105.1
L-serine ammonia-lyase alpha subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.960
KRK94106.1
L-serine ammonia-lyase beta subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.960
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
   
 
 0.958
KRK94519.1
O-acetylhomoserine (thiol)-lyase.
    
  0.957
KRK95512.1
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase.
   
 
 0.863
KRK96134.1
Hypothetical protein.
   
 
 0.863
KRK95537.1
Aspartate kinase; Belongs to the aspartokinase family.
  
 0.860
Your Current Organism:
Lactobacillus acidifarinae
NCBI taxonomy Id: 1423715
Other names: L. acidifarinae DSM 19394, Lactobacillus acidifarinae DSM 19394
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.