STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRK75085.1Septum site-determining protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization. (222 aa)    
Predicted Functional Partners:
KRK75086.1
Septum formation-inhibiting ATPase, ATPase ParA-type.
 
 
 0.999
KRK75084.1
Rod shape-determining protein MreD.
 
  
 0.973
KRK75083.1
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
  
 0.953
KRK75082.1
Rod shape-determining protein MreB.
 
  
 0.876
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
   
 
 0.836
KRK75100.1
Cell-division initiation protein (septum placement).
 
  
 0.786
KRK76360.1
Drug Na(+) antiporter (drug efflux pump).
 
    0.715
KRK75255.1
Lysophospholipase l1-like esterase.
  
    0.699
mltG
Hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
 
    0.647
sepF
Cell division protein sepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
  
 0.634
Your Current Organism:
Lactobacillus alimentarius
NCBI taxonomy Id: 1423720
Other names: L. alimentarius DSM 20249, Lactobacillus alimentarius DSM 20249
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.