STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APT19211.1Hypothetical protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. (114 aa)    
Predicted Functional Partners:
recU
Holliday junction resolvase RecU; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
 
   
 0.845
APT19214.1
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.802
ezrA
Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
 
 0.798
APT17924.1
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.705
APT17890.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.698
APT19099.1
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.690
divIB
Hypothetical protein; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
 
   
 0.662
APT17959.1
Cell division protein FtsI; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.653
APT19007.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.620
APT18914.1
Transcriptional regulator Spx; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family.
  
    0.589
Your Current Organism:
Lactobacillus amylophilus
NCBI taxonomy Id: 1423721
Other names: L. amylophilus DSM 20533 = JCM 1125, Lactobacillus amylophilus DSM 20533, Lactobacillus amylophilus DSM 20533 = JCM 1125
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