STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mprFHypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. (345 aa)    
Predicted Functional Partners:
KRM94904.1
Glycosyl transferase group 1.
 
    0.946
KRM94905.1
Glycosyltransferase.
 
    0.880
KRM95630.1
Hypothetical protein.
  
     0.727
KRM95513.1
Hypothetical protein.
  
     0.658
KRM94902.1
Hypothetical protein.
       0.643
KRM94901.1
Sulfatase family protein.
 
    0.612
KRM96170.1
IpaB EvcA family protein.
  
     0.603
KRM95536.1
hemolysinC family Mg(2+) Co(2+) transport protein.
  
     0.553
KRM97005.1
YycH family protein.
  
   
 0.522
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.520
Your Current Organism:
Lactobacillus aquaticus
NCBI taxonomy Id: 1423725
Other names: L. aquaticus DSM 21051, Lactobacillus aquaticus DSM 21051
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.