STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
larCHypothetical protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family. (411 aa)    
Predicted Functional Partners:
KRM95302.1
PP family ATPase.
  
 0.997
KRM95304.1
NCAIR mutase (PurE)-related protein.
 
  
 0.993
KRM95305.1
Hypothetical protein.
 
  
 0.986
KRM95306.1
cAMP-binding protein.
 
  
 0.927
KRM95301.1
Glycerol uptake facilitator related permease (major Intrinsic protein family); Belongs to the MIP/aquaporin (TC 1.A.8) family.
     
 0.785
pyrG
CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
 
      0.636
Your Current Organism:
Lactobacillus aquaticus
NCBI taxonomy Id: 1423725
Other names: L. aquaticus DSM 21051, Lactobacillus aquaticus DSM 21051
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