STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRM95094.1NTP pyrophosphohydrolase. (152 aa)    
Predicted Functional Partners:
folE
GTP cyclohydrolase I.
  
 
 0.908
KRM96354.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
  0.852
cinA
Competence damage-inducible protein A; Belongs to the CinA family.
    
  0.850
guaA
Bifunctional gmp synthase glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.
    
  0.731
KRM96305.1
Acetyltransferase.
 
    0.635
KRM95093.1
Hypothetical protein.
       0.491
KRM95095.1
Hypothetical protein.
       0.485
menG
Ubiquinone menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
  
     0.456
KRM95764.1
HAM1 protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 
 0.451
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.434
Your Current Organism:
Lactobacillus aquaticus
NCBI taxonomy Id: 1423725
Other names: L. aquaticus DSM 21051, Lactobacillus aquaticus DSM 21051
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.