STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (267 aa)    
Predicted Functional Partners:
proB
Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.873
KRK39856.1
Ornithine cyclodeaminase.
   
 
 0.836
KRK40648.1
Proline iminopeptidase; Releases the N-terminal proline from various substrates. Belongs to the peptidase S33 family.
    
  0.809
KRK34627.1
Prolyl aminopeptidase; Releases the N-terminal proline from various substrates. Belongs to the peptidase S33 family.
    
  0.809
KRK32799.1
Formate acetyltransferase.
    
  0.784
KRK39939.1
Proline racemase; Belongs to the proline racemase family.
    
 0.692
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.686
KRK32801.1
Hypothetical protein.
 
     0.565
KRK40634.1
Glutamate synthase large subunit.
     
 0.494
KRK32800.1
Formate acetyltransferase activating enzyme.
       0.464
Your Current Organism:
Lactobacillus bifermentans
NCBI taxonomy Id: 1423726
Other names: L. bifermentans DSM 20003, Lactobacillus bifermentans DSM 20003
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.