STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRM92005.1Hypothetical protein. (90 aa)    
Predicted Functional Partners:
KRM92900.1
Plasmid replication initiation protein.
  
     0.766
KRM90930.1
Hypothetical protein.
 
     0.681
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.535
KRM92004.1
Orf-12.
       0.515
hslV
ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
  
    0.487
KRM92003.1
Hypothetical protein.
       0.458
KRM90642.1
single-stranded-DNA-specific exonuclease.
  
  
 0.444
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.424
KRM90422.1
Amidophosphoribosyltransferase.
   
    0.416
Your Current Organism:
Lactobacillus cacaonum
NCBI taxonomy Id: 1423729
Other names: L. cacaonum DSM 21116, Lactobacillus cacaonum DSM 21116
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.