STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRL00478.1Malate dehydrogenase. (539 aa)    
Predicted Functional Partners:
KRL01240.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.924
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.857
KRL01388.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 0.846
KRL01674.1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.815
KRL01519.1
Formate acetyltransferase.
   
 
 0.811
KRL02163.1
Pyruvate dehydrogenase E1 component beta subunit.
   
 
 0.806
pdhA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
   
 
 0.789
KRL03595.1
Hypothetical protein.
    
  0.782
KRL00479.1
Di- and tricarboxylate transporter.
  
  
 0.776
leuD
Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
  
 
 0.720
Your Current Organism:
Lactobacillus capillatus
NCBI taxonomy Id: 1423731
Other names: L. capillatus DSM 19910, Lactobacillus capillatus DSM 19910
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.