KRM30607.1 protein (Lactobacillus composti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

KRM30607.1

Citrate lyase, alpha subunit. (516 aa)

Predicted Functional Partners:

citD-2

0.987

KRM30606.1

0.978

KRM30476.1

0.953

KRM30474.1

0.949

citD

0.944

KRM34220.1

0.944

KRM30478.1

0.931

citG

0.886

KRM30480.1

0.584

KRM30604.1

0.558

Your Current Organism:

Lactobacillus composti

NCBI taxonomy Id: 1423734
Other names: L. composti DSM 18527 = JCM 14202, Lactobacillus composti DSM 18527, Lactobacillus composti DSM 18527 = JCM 14202, Lactobacillus composti JCM 14202, Lactobacillus composti JCM 14202 = DSM 18527

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KRM30474.1	KRM30476.1	FC83_GL001605	FC83_GL001607	phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase).	citE protein; Belongs to the HpcH/HpaI aldolase family.	0.987
KRM30474.1	KRM30478.1	FC83_GL001605	FC83_GL001609	phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase).	citC protein; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase.	0.975
KRM30474.1	KRM30480.1	FC83_GL001605	FC83_GL001611	phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase).	Citrate lyase regulator.	0.640
KRM30474.1	KRM30606.1	FC83_GL001605	FC83_GL001742	phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase).	Citrate (pro-3S)-lyase; Belongs to the HpcH/HpaI aldolase family.	0.948
KRM30474.1	KRM30607.1	FC83_GL001605	FC83_GL001743	phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase).	Citrate lyase, alpha subunit.	0.949
KRM30474.1	KRM34220.1	FC83_GL001605	FC83_GL002211	phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase).	Hypothetical protein.	0.926
KRM30474.1	citD	FC83_GL001605	FC83_GL001608	phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase).	Citrate lyase acyl carrier protein; Covalent carrier of the coenzyme of citrate lyase.	0.975
KRM30474.1	citD-2	FC83_GL001605	FC83_GL001741	phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase).	Hypothetical protein; Covalent carrier of the coenzyme of citrate lyase.	0.902
KRM30474.1	citG	FC83_GL001605	FC83_GL002202	phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase).	Triphosphoribosyl-dephospho-coenzymeA synthase.	0.994
KRM30476.1	KRM30474.1	FC83_GL001607	FC83_GL001605	citE protein; Belongs to the HpcH/HpaI aldolase family.	phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase).	0.987
KRM30476.1	KRM30478.1	FC83_GL001607	FC83_GL001609	citE protein; Belongs to the HpcH/HpaI aldolase family.	citC protein; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase.	0.997
KRM30476.1	KRM30480.1	FC83_GL001607	FC83_GL001611	citE protein; Belongs to the HpcH/HpaI aldolase family.	Citrate lyase regulator.	0.702
KRM30476.1	KRM30607.1	FC83_GL001607	FC83_GL001743	citE protein; Belongs to the HpcH/HpaI aldolase family.	Citrate lyase, alpha subunit.	0.953
KRM30476.1	KRM34220.1	FC83_GL001607	FC83_GL002211	citE protein; Belongs to the HpcH/HpaI aldolase family.	Hypothetical protein.	0.994
KRM30476.1	citD	FC83_GL001607	FC83_GL001608	citE protein; Belongs to the HpcH/HpaI aldolase family.	Citrate lyase acyl carrier protein; Covalent carrier of the coenzyme of citrate lyase.	0.998
KRM30476.1	citD-2	FC83_GL001607	FC83_GL001741	citE protein; Belongs to the HpcH/HpaI aldolase family.	Hypothetical protein; Covalent carrier of the coenzyme of citrate lyase.	0.949
KRM30476.1	citG	FC83_GL001607	FC83_GL002202	citE protein; Belongs to the HpcH/HpaI aldolase family.	Triphosphoribosyl-dephospho-coenzymeA synthase.	0.925
KRM30478.1	KRM30474.1	FC83_GL001609	FC83_GL001605	citC protein; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase.	phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase).	0.975
KRM30478.1	KRM30476.1	FC83_GL001609	FC83_GL001607	citC protein; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase.	citE protein; Belongs to the HpcH/HpaI aldolase family.	0.997
KRM30478.1	KRM30480.1	FC83_GL001609	FC83_GL001611	citC protein; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase.	Citrate lyase regulator.	0.709

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

53

average node degree:

9.64

avg. local clustering coefficient:

0.962

expected number of edges:

11

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:1902600

Proton transmembrane transport

4 of 26

1.73

1.4

0.0011

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004129

Cytochrome-c oxidase activity

3 of 5

2.32

1.9

0.00025

GO:0015453

Oxidoreduction-driven active transmembrane transporter activity

4 of 22

1.8

1.73

0.00020

GO:0015078

Proton transmembrane transporter activity

4 of 28

1.7

1.63

0.00025

GO:0009055

Electron transfer activity

5 of 49

1.55

1.58

0.00015

GO:0022853

Active ion transmembrane transporter activity

4 of 32

1.64

1.58

0.00026

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016021

Integral component of membrane

11 of 819

0.67

0.63

6.13e-06

GO:0005886

Plasma membrane

8 of 616

0.66

0.52

0.0017

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2400

Oxidative phosphorylation, and SLBB domain

10 of 42

1.92

5.35

3.99e-16

CL:2453

Mixed, incl. Respiratory chain, and Peptidase M16 inactive domain

6 of 12

2.24

4.46

4.02e-10

CL:2396

Mixed, incl. Oxidative phosphorylation, and Heme binding

11 of 77

1.7

4.27

3.99e-16

CL:2457

Respiratory chain, and Rieske [2Fe-2S] domain

5 of 7

2.4

4.06

8.85e-09

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00190

Oxidative phosphorylation

9 of 64

1.69

3.71

1.21e-12

map01100

Metabolic pathways

10 of 1522

0.36

0.26

0.0406

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0070469

Respirasome

3 of 30

1.54

0.89

0.0134

GOCC:0031975

Envelope

4 of 116

1.08

0.62

0.0247

GOCC:0016020

Membrane

9 of 721

0.64

0.48

0.0034

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0249

Electron transport

3 of 12

1.94

1.51

0.00096

KW-0186

Copper

2 of 2

2.54

1.48

0.0019

KW-0350

Heme biosynthesis

2 of 3

2.37

1.39

0.0026

KW-0679

Respiratory chain

2 of 6

2.07

1.16

0.0062

KW-1133

Transmembrane helix

9 of 648

0.69

0.55

0.00096

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (26%) [HD]

Permalink

Network

Neighborhood

Databases

Fusion

Textmining

Cooccurrence

Experiments

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About