KRM33114.1 protein (Lactobacillus composti) - STRING interaction network

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second shell of interactors

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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Score

KRM33114.1

Acetoin pyruvate dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase. (464 aa)

Predicted Functional Partners:

KRM30864.1

0.981

KRM33111.1

0.981

KRM33112.1

0.959

KRM36613.1

0.933

KRM30614.1

0.931

KRM30660.1

0.931

KRM36625.1

0.880

KRM30863.1

0.873

KRM36614.1

0.867

KRM33113.1

0.862

Your Current Organism:

Lactobacillus composti

NCBI taxonomy Id: 1423734
Other names: L. composti DSM 18527 = JCM 14202, Lactobacillus composti DSM 18527, Lactobacillus composti DSM 18527 = JCM 14202, Lactobacillus composti JCM 14202, Lactobacillus composti JCM 14202 = DSM 18527

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KRM30614.1	KRM30660.1	FC83_GL001750	FC83_GL001796	Pyruvate flavodoxin ferredoxin oxidoreductase family protein.	Pyruvate flavodoxin ferredoxin oxidoreductase family protein.	0.999
KRM30614.1	KRM30863.1	FC83_GL001750	FC83_GL001424	Pyruvate flavodoxin ferredoxin oxidoreductase family protein.	Pyruvate dehydrogenase E1 component beta subunit.	0.960
KRM30614.1	KRM30864.1	FC83_GL001750	FC83_GL001425	Pyruvate flavodoxin ferredoxin oxidoreductase family protein.	Branched-chain alpha-keto acid dehydrogenase subunit E2.	0.956
KRM30614.1	KRM33111.1	FC83_GL001750	FC83_GL003192	Pyruvate flavodoxin ferredoxin oxidoreductase family protein.	Branched-chain alpha-keto acid, E2 component, dihydrolipoamide acetyltransferase.	0.956
KRM30614.1	KRM33112.1	FC83_GL001750	FC83_GL003193	Pyruvate flavodoxin ferredoxin oxidoreductase family protein.	Acetoin dehydrogenase complex.	0.960
KRM30614.1	KRM33113.1	FC83_GL001750	FC83_GL003194	Pyruvate flavodoxin ferredoxin oxidoreductase family protein.	Branched-chain alpha-keto acid dehydrogenase, E1 component, subunit alpha.	0.947
KRM30614.1	KRM33114.1	FC83_GL001750	FC83_GL003195	Pyruvate flavodoxin ferredoxin oxidoreductase family protein.	Acetoin pyruvate dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase.	0.931
KRM30614.1	KRM36613.1	FC83_GL001750	FC83_GL002487	Pyruvate flavodoxin ferredoxin oxidoreductase family protein.	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.	0.956
KRM30614.1	KRM36614.1	FC83_GL001750	FC83_GL002488	Pyruvate flavodoxin ferredoxin oxidoreductase family protein.	Pyruvate dehydrogenase (acetyl-transferring).	0.960
KRM30614.1	KRM36625.1	FC83_GL001750	FC83_GL002499	Pyruvate flavodoxin ferredoxin oxidoreductase family protein.	Glutamate synthase large subunit.	0.971
KRM30660.1	KRM30614.1	FC83_GL001796	FC83_GL001750	Pyruvate flavodoxin ferredoxin oxidoreductase family protein.	Pyruvate flavodoxin ferredoxin oxidoreductase family protein.	0.999
KRM30660.1	KRM30863.1	FC83_GL001796	FC83_GL001424	Pyruvate flavodoxin ferredoxin oxidoreductase family protein.	Pyruvate dehydrogenase E1 component beta subunit.	0.960
KRM30660.1	KRM30864.1	FC83_GL001796	FC83_GL001425	Pyruvate flavodoxin ferredoxin oxidoreductase family protein.	Branched-chain alpha-keto acid dehydrogenase subunit E2.	0.956
KRM30660.1	KRM33111.1	FC83_GL001796	FC83_GL003192	Pyruvate flavodoxin ferredoxin oxidoreductase family protein.	Branched-chain alpha-keto acid, E2 component, dihydrolipoamide acetyltransferase.	0.956
KRM30660.1	KRM33112.1	FC83_GL001796	FC83_GL003193	Pyruvate flavodoxin ferredoxin oxidoreductase family protein.	Acetoin dehydrogenase complex.	0.960
KRM30660.1	KRM33113.1	FC83_GL001796	FC83_GL003194	Pyruvate flavodoxin ferredoxin oxidoreductase family protein.	Branched-chain alpha-keto acid dehydrogenase, E1 component, subunit alpha.	0.947
KRM30660.1	KRM33114.1	FC83_GL001796	FC83_GL003195	Pyruvate flavodoxin ferredoxin oxidoreductase family protein.	Acetoin pyruvate dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase.	0.931
KRM30660.1	KRM36613.1	FC83_GL001796	FC83_GL002487	Pyruvate flavodoxin ferredoxin oxidoreductase family protein.	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.	0.956
KRM30660.1	KRM36614.1	FC83_GL001796	FC83_GL002488	Pyruvate flavodoxin ferredoxin oxidoreductase family protein.	Pyruvate dehydrogenase (acetyl-transferring).	0.960
KRM30660.1	KRM36625.1	FC83_GL001796	FC83_GL002499	Pyruvate flavodoxin ferredoxin oxidoreductase family protein.	Glutamate synthase large subunit.	0.971

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Network Stats

number of nodes:

5

number of edges:

7

average node degree:

2.8

avg. local clustering coefficient:

0.9

expected number of edges:

5

PPI enrichment p-value:

0.255

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006351

Transcription, DNA-templated

6 of 16

2.18

3.97

4.08e-09

GO:0031564

Transcription antitermination

3 of 3

2.61

2.28

5.92e-05

GO:0006353

DNA-templated transcription, termination

3 of 4

2.48

2.24

6.48e-05

GO:0034654

Nucleobase-containing compound biosynthetic process

7 of 165

1.24

1.43

1.06e-05

GO:0010467

Gene expression

7 of 235

1.08

1.1

6.48e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003899

DNA-directed 5-3 RNA polymerase activity

3 of 9

2.13

1.41

0.0020

GO:0003676

Nucleic acid binding

7 of 589

0.68

0.42

0.0294

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000428

DNA-directed RNA polymerase complex

3 of 10

2.09

1.7

0.00048

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1641

Transcription, DNA-templated, and SNF2, N-terminal

6 of 14

2.24

4.22

1.51e-09

CL:1659

DNA-templated transcription, termination

3 of 5

2.39

2.19

7.37e-05

CL:1645

RNA polymerase

3 of 5

2.39

2.19

7.37e-05

CL:1417

Translation, and Purine nucleoside triphosphate biosynthetic process

7 of 126

1.35

1.73

2.49e-06

CL:1369

Mixed, incl. NAD(P)+ transhydrogenase activity, and NAD synthase

2 of 7

2.07

0.92

0.0188

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03020

RNA polymerase

3 of 5

2.39

2.18

7.51e-05

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-9635486

Infection with Mycobacterium tuberculosis

3 of 84

1.16

0.65

0.0270

MAP-5663205

Infectious disease

3 of 88

1.14

0.64

0.0270

MAP-1643685

Disease

3 of 93

1.12

0.63

0.0270

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0008023

Transcription elongation factor complex

2 of 2

2.61

1.11

0.0097

GOCC:0000428

DNA-directed RNA polymerase complex

3 of 50

1.39

0.74

0.0237

GOCC:0005622

Intracellular

10 of 1477

0.44

0.32

0.0179

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0889

Transcription antitermination

3 of 3

2.61

2.35

4.47e-05

KW-0240

DNA-directed RNA polymerase

3 of 6

2.31

2.19

6.59e-05

KW-0804

Transcription

6 of 123

1.3

1.41

4.47e-05

KW-0806

Transcription termination

2 of 3

2.43

1.37

0.0029

KW-0548

Nucleotidyltransferase

3 of 46

1.42

0.93

0.0082

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