STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRL65453.1Guanylate kinase. (185 aa)    
Predicted Functional Partners:
guaA
Bifunctional GMP synthase glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.977
KRL64410.1
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
     
 0.956
KRL64409.1
Ribonucleoside-diphosphate reductase.
     
 0.955
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 
 0.946
KRL70000.1
Adenine phosphoribosyltransferase.
   
 
 0.943
xpt
Adenine guanine phosphoribosyltransferase family protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
   
 
 0.943
KRL64246.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.938
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
  
 
0.934
guaC
Guanosine 5-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
 
  
 0.928
KRL64276.1
GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.924
Your Current Organism:
Lactobacillus diolivorans
NCBI taxonomy Id: 1423739
Other names: L. diolivorans DSM 14421, Lactobacillus diolivorans DSM 14421
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