STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhAPyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (373 aa)    
Predicted Functional Partners:
KRL65729.1
Pyruvate dehydrogenase (acetyl-transferring).
 0.999
KRL65730.1
Dihydrolipoyllysine-residue acetyltransferase.
 0.999
KRL65731.1
Dihydrolipoamide dehydrogenase.
 
 0.996
KRL64246.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.963
KRL64896.1
Dihydrolipoyl dehydrogenase.
 
 
 0.933
KRL62273.1
Pyridine nucleotide-disulfide oxidoreductase.
 
 
 0.933
KRL68599.1
Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
    
 0.932
zwf
Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
     
 0.928
KRL67438.1
Keto-hydroxyglutarate-aldolase keto-deoxy-phosphogluconate aldolase.
     
 0.922
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
   
 
 0.877
Your Current Organism:
Lactobacillus diolivorans
NCBI taxonomy Id: 1423739
Other names: L. diolivorans DSM 14421, Lactobacillus diolivorans DSM 14421
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