STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gtfBGlycosyl transferase; Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. A stabilizing protein that is part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. The GtfA-GtfB complex adds GlcNAc from UDP-GlcNAc to the substrate protein, attaching the first sugar residue. Stabilizes the glycosylation activity of GtfA. Has no N-acetylglucosaminyl transferase activity on its own. (443 aa)    
Predicted Functional Partners:
gtfA
Gfta-like poly(glycerol-phosphate) alpha-glucosyltransferase; Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. Catalyzes the first step in glycosylation by transferring N-acetylglucosamine from UDP-GlcNAc to serine residues in the substrate protein. Part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon.
   
 0.975
KRL80254.1
Hypothetical protein.
   
 
 0.950
KRL80256.1
Accessory secretory protein asp1.
   
 
 0.949
KRL80255.1
Accessory secretory protein Asp2.
   
 
 0.931
KRL77108.1
Hypothetical protein.
   
 
 0.845
secA
Preprotein translocase subunit seca; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
   
 
 0.822
KRL80249.1
Hypothetical protein.
    
  0.819
KRL79706.1
Glycosyltransferase.
   
 
 0.788
KRL77111.1
Lipopolysaccharide biosynthesis protein.
   
 
 0.788
KRL76823.1
Glycosyltransferase, group 1 family protein.
   
 
 0.788
Your Current Organism:
Lactobacillus equi
NCBI taxonomy Id: 1423740
Other names: L. equi DSM 15833 = JCM 10991, Lactobacillus equi DSM 15833, Lactobacillus equi DSM 15833 = JCM 10991, Lactobacillus equi JCM 10991, Lactobacillus equi JCM 10991 = DSM 15833
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.