STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. (468 aa)    
Predicted Functional Partners:
KRM09629.1
Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
 
 0.995
guaA
Bifunctional GMP synthase glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.924
KRM05131.1
NADPH-dependent glutamate synthase (large subunit).
    
  0.896
KRM01357.1
Guanylate kinase.
  
  
 0.895
purH
Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase.
   
  0.893
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.888
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
  
 0.886
KRM04646.1
Purine nucleosidase.
  
  0.883
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 
  0.879
KRM09525.1
Adenine guanine phosphoribosyltransferase family protein.
   
 
  0.879
Your Current Organism:
Lactobacillus farraginis
NCBI taxonomy Id: 1423743
Other names: L. farraginis DSM 18382 = JCM 14108, Lactobacillus farraginis DSM 18382, Lactobacillus farraginis DSM 18382 = JCM 14108, Lactobacillus farraginis JCM 14108, Lactobacillus farraginis JCM 14108 = DSM 18382
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