STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRN03541.1Na(+) H(+) antiporter. (393 aa)    
Predicted Functional Partners:
KRN04783.1
NAD(P)H dehydrogenase (quinone).
  
 
 0.840
guaB
IMP dehydrogenase GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.805
KRN04002.1
NhaP-type Na+ H+ and K+ H+ antiporter.
   
 
 0.773
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
 
 0.723
KRN04757.1
GntR family transcriptional regulator.
  
  
 0.708
KRN04454.1
Cation transport ATPase.
  
 
 0.698
KRN04335.1
Magnesium-translocating P-type ATPase.
  
 
 0.698
KRN04091.1
Cation transporting p-type atpase.
  
 
 0.698
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.683
KRN04522.1
Hypothetical protein.
     
 0.673
Your Current Organism:
Lactobacillus floricola
NCBI taxonomy Id: 1423744
Other names: L. floricola DSM 23037 = JCM 16512, Lactobacillus floricola DSM 23037, Lactobacillus floricola DSM 23037 = JCM 16512, Lactobacillus floricola JCM 16512, Lactobacillus floricola JCM 16512 = DSM 23037, Lactobacillus floricola Ryu1-2, Lactobacillus sp. Ryu1-2
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