STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nthEndoIII-related endonuclease; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (209 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 
 0.917
KRN03738.1
DNA replication protein DnaD.
  
  
 0.879
nfo
Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
  
 
 0.849
dinG
Rad3-related DNA helicase; 3'-5' exonuclease.
  
  
 0.822
KRN03783.1
single-stranded-DNA-specific exonuclease RecJ.
  
  
 0.804
ung
uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
  
 0.799
KRN03737.1
Transport protein.
       0.682
KRN04791.1
A G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
 
 
 0.663
mutL
DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
   
 
 0.652
KRN03739.1
Hypothetical protein.
       0.601
Your Current Organism:
Lactobacillus floricola
NCBI taxonomy Id: 1423744
Other names: L. floricola DSM 23037 = JCM 16512, Lactobacillus floricola DSM 23037, Lactobacillus floricola DSM 23037 = JCM 16512, Lactobacillus floricola JCM 16512, Lactobacillus floricola JCM 16512 = DSM 23037, Lactobacillus floricola Ryu1-2, Lactobacillus sp. Ryu1-2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.