STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (369 aa)    
Predicted Functional Partners:
thiI
Thiamine biosynthesis tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
 
 0.865
KRL58492.1
PP-loop superfamily ATP-binding protein.
    
 0.854
mnmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
 0.794
KRL58491.1
Hypothetical protein.
  
  
 0.705
metG
metS protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
  
  
 0.681
KRL59582.1
Hypothetical protein; Belongs to the ribF family.
 
    0.665
rpmA
rpmA protein; Belongs to the bacterial ribosomal protein bL27 family.
  
  
 0.653
KRL58490.1
Hypothetical protein.
       0.629
KRL61495.1
Hypothetical protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.629
ddl
D-alanine--D-alanine ligase family protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
  
  
 0.628
Your Current Organism:
Lactobacillus fuchuensis
NCBI taxonomy Id: 1423747
Other names: L. fuchuensis DSM 14340 = JCM 11249, Lactobacillus fuchuensis DSM 14340, Lactobacillus fuchuensis DSM 14340 = JCM 11249, Lactobacillus fuchuensis JCM 11249, Lactobacillus fuchuensis JCM 11249 = DSM 14340
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.