STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRL59381.1Glycine cleavage H-family protein. (102 aa)    
Predicted Functional Partners:
glyA
glyA protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.986
KRL58470.1
Dihydrolipoyl dehydrogenase.
 
  
 0.971
KRL61547.1
Hypothetical protein.
 
 
 0.951
KRL58471.1
pdhC protein.
  
 0.942
KRL62083.1
lplA protein.
 
 
 0.931
KRL58826.1
glnA protein.
   
 
 0.925
KRL59382.1
Cell cycle family protein; Belongs to the SEDS family.
  
  
 0.924
KRL58472.1
Pyruvate dehydrogenase E1 component subunit beta.
   
 
 0.919
purQ
purQ protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia mo [...]
  
 
  0.918
KRL59344.1
Glutathione-disulfide reductase.
 
  
 0.880
Your Current Organism:
Lactobacillus fuchuensis
NCBI taxonomy Id: 1423747
Other names: L. fuchuensis DSM 14340 = JCM 11249, Lactobacillus fuchuensis DSM 14340, Lactobacillus fuchuensis DSM 14340 = JCM 11249, Lactobacillus fuchuensis JCM 11249, Lactobacillus fuchuensis JCM 11249 = DSM 14340
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