node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KRN09573.1 | KRN13962.1 | FC38_GL001391 | FC38_GL001724 | 5-nucleotidase; Belongs to the 5'-nucleotidase family. | dUTPase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 0.938 |
KRN09573.1 | KRN14417.1 | FC38_GL001391 | FC38_GL001078 | 5-nucleotidase; Belongs to the 5'-nucleotidase family. | Deoxycytidylate deaminase. | 0.940 |
KRN09573.1 | deoD | FC38_GL001391 | FC38_GL000877 | 5-nucleotidase; Belongs to the 5'-nucleotidase family. | Purine nucleoside phosphorylase. | 0.968 |
KRN09573.1 | prfA | FC38_GL001391 | FC38_GL000066 | 5-nucleotidase; Belongs to the 5'-nucleotidase family. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.455 |
KRN09573.1 | tdk | FC38_GL001391 | FC38_GL000067 | 5-nucleotidase; Belongs to the 5'-nucleotidase family. | Thymidine kinase. | 0.940 |
KRN09573.1 | thyA | FC38_GL001391 | FC38_GL000586 | 5-nucleotidase; Belongs to the 5'-nucleotidase family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.940 |
KRN09573.1 | tmk | FC38_GL001391 | FC38_GL001704 | 5-nucleotidase; Belongs to the 5'-nucleotidase family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.944 |
KRN09573.1 | upp | FC38_GL001391 | FC38_GL000063 | 5-nucleotidase; Belongs to the 5'-nucleotidase family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.938 |
KRN13962.1 | KRN09573.1 | FC38_GL001724 | FC38_GL001391 | dUTPase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 5-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.938 |
KRN13962.1 | KRN14417.1 | FC38_GL001724 | FC38_GL001078 | dUTPase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Deoxycytidylate deaminase. | 0.963 |
KRN13962.1 | tdk | FC38_GL001724 | FC38_GL000067 | dUTPase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Thymidine kinase. | 0.976 |
KRN13962.1 | thyA | FC38_GL001724 | FC38_GL000586 | dUTPase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.988 |
KRN13962.1 | tmk | FC38_GL001724 | FC38_GL001704 | dUTPase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.964 |
KRN14417.1 | KRN09573.1 | FC38_GL001078 | FC38_GL001391 | Deoxycytidylate deaminase. | 5-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.940 |
KRN14417.1 | KRN13962.1 | FC38_GL001078 | FC38_GL001724 | Deoxycytidylate deaminase. | dUTPase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 0.963 |
KRN14417.1 | tdk | FC38_GL001078 | FC38_GL000067 | Deoxycytidylate deaminase. | Thymidine kinase. | 0.956 |
KRN14417.1 | thyA | FC38_GL001078 | FC38_GL000586 | Deoxycytidylate deaminase. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.958 |
KRN14417.1 | tmk | FC38_GL001078 | FC38_GL001704 | Deoxycytidylate deaminase. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.953 |
KRN14772.1 | KRN14773.1 | FC38_GL000064 | FC38_GL000065 | Sua5 family translation factor; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Protoporphyrinogen oxidase. | 0.952 |
KRN14772.1 | prfA | FC38_GL000064 | FC38_GL000066 | Sua5 family translation factor; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.824 |