STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mprFHypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. (341 aa)    
Predicted Functional Partners:
KRN13971.1
Glycosyl transferase CpoA.
 
  
 0.907
KRN13972.1
Group 1 glycosyl transferase.
 
  
 0.890
KRN14319.1
Hypothetical protein.
 
     0.724
KRN13969.1
Sulfatase domain protein.
  
  
 0.684
KRN14781.1
Glycopeptide antibiotics resistance protein.
  
   
 0.579
KRN14574.1
Hypothetical protein.
  
     0.570
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
   
 0.568
KRN14717.1
TPR repeat protein.
  
     0.543
KRN14138.1
Hypothetical protein.
 
  
 0.543
KRN11695.1
Diacylglycerol kinase.
  
 
  0.525
Your Current Organism:
Lactobacillus gigeriorum
NCBI taxonomy Id: 1423751
Other names: L. gigeriorum DSM 23908 = CRBIP 24.85, Lactobacillus gigeriorum 202, Lactobacillus gigeriorum CRBIP 24.85, Lactobacillus gigeriorum CRBIP 24.85 = DSM 23908, Lactobacillus gigeriorum DSM 23908, Lactobacillus gigeriorum DSM 23908 = CRBIP 24.85
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