STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRN13856.1Dihydrolipoyl dehydrogenase. (443 aa)    
Predicted Functional Partners:
KRN09985.1
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 0.995
KRN09984.1
Pyruvate dehydrogenase complex, E1 component, beta subunit.
 
 0.990
KRN09983.1
pdhA protein.
 
 
 0.958
KRN12825.1
Thioredoxin; Belongs to the thioredoxin family.
  
 0.933
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.905
KRN14130.1
Glutamine synthetase.
  
 
 0.903
KRN09993.1
Lipoate-protein ligase A.
 
 
 0.764
prs
Ribose-p-pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.756
KRN13770.1
Ribose-p pyrokinase.
   
 0.756
KRN14848.1
Thioredoxin reductase.
 
 0.737
Your Current Organism:
Lactobacillus gigeriorum
NCBI taxonomy Id: 1423751
Other names: L. gigeriorum DSM 23908 = CRBIP 24.85, Lactobacillus gigeriorum 202, Lactobacillus gigeriorum CRBIP 24.85, Lactobacillus gigeriorum CRBIP 24.85 = DSM 23908, Lactobacillus gigeriorum DSM 23908, Lactobacillus gigeriorum DSM 23908 = CRBIP 24.85
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