STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ezrASeptation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. (585 aa)    
Predicted Functional Partners:
gpsB
Cell division protein GpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
  
 
 0.785
divIB
Cell division septal protein; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
  
   
 0.775
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
      
 0.759
ftsA
ATPase for cell division; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
  
 
 0.740
KRL93148.1
Metal-binding protein.
  
     0.736
KRL93163.1
Replication initiation membrane attachment protein.
 
     0.734
KRL94839.1
Hypothetical protein; Belongs to the UPF0473 family.
  
     0.719
KRL95153.1
Dithiol-disulfide isomerase.
  
     0.704
KRL94838.1
Hypothetical protein.
  
 
 
 0.703
KRL97663.1
Hypothetical protein.
  
     0.693
Your Current Organism:
Lactobacillus hammesii
NCBI taxonomy Id: 1423753
Other names: L. hammesii DSM 16381, Lactobacillus hammesii DSM 16381
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