STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRM40530.1Pectin acetylesterase. (282 aa)    
Predicted Functional Partners:
KRM40531.1
Hypothetical protein.
 
     0.806
KRM40734.1
Nucleoside-diphosphate-sugar epimerase.
  
   0.748
acpP
Hypothetical protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
 0.696
dltC
Hypothetical protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
   
 0.696
KRM41133.1
Protease.
    
 
 0.656
KRM41134.1
Protease.
    
 
 0.656
KRM40528.1
AraC family transcriptional regulator.
 
 
  0.653
KRM40529.1
cephalosporin-C deacetylase.
 
     0.568
dnaJ
Chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...]
   
   0.566
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
    
   0.561
Your Current Organism:
Lactobacillus hamsteri
NCBI taxonomy Id: 1423754
Other names: L. hamsteri DSM 5661 = JCM 6256, Lactobacillus hamsteri DSM 5661, Lactobacillus hamsteri DSM 5661 = JCM 6256, Lactobacillus hamsteri JCM 6256, Lactobacillus hamsteri JCM 6256 = DSM 5661
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.