STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRM19102.1Folylpolyglutamate synthase dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. (433 aa)    
Predicted Functional Partners:
KRM18970.1
Dihydrofolate reductase.
     
 0.970
KRM19101.1
DNA repair protein; Belongs to the UPF0758 family.
  
  
 0.802
valS
Valyl-trna synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
 
  
 0.784
hisS
histidine--tRNA ligase.
     
 0.634
KRM19100.1
Hypothetical protein.
       0.634
guaA
GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.
 
  
 0.625
KRM19099.1
Rod shape-determining protein MreB.
       0.605
KRM18857.1
Phosphopantothenoylcysteine decarboxylase phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
     
 0.556
KRM17887.1
Integral membrane protein.
   
    0.474
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
 
   
 0.453
Your Current Organism:
Lactobacillus hayakitensis
NCBI taxonomy Id: 1423755
Other names: L. hayakitensis DSM 18933 = JCM 14209, Lactobacillus hayakitensis DSM 18933, Lactobacillus hayakitensis DSM 18933 = JCM 14209, Lactobacillus hayakitensis JCM 14209, Lactobacillus hayakitensis JCM 14209 = DSM 18933
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