STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRM19655.1Na+ h+ antiporter; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (618 aa)    
Predicted Functional Partners:
KRM20175.1
H(+)-transporting two-sector ATPase.
  
 
 0.887
KRM20205.1
NAD(P)H dehydrogenase YwrO.
  
 
 0.723
KRM18357.1
Voltage-gated chloride channel family protein.
 
   
 0.659
KRM18860.1
16s ribosomal rna m(5)c 967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
   0.625
guaB
Inositol-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.618
KRM19657.1
DedA protein.
  
    0.553
KRM19971.1
Bifunctional acetaldehyde-coa alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.543
dnaJ
Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...]
   
 
 0.512
KRM19223.1
Mg2+ transporter; Acts as a magnesium transporter.
     
 0.480
KRM19884.1
Potassium efflux system kefa protein small-conductance mechanosensitive channel.
     
 0.478
Your Current Organism:
Lactobacillus hayakitensis
NCBI taxonomy Id: 1423755
Other names: L. hayakitensis DSM 18933 = JCM 14209, Lactobacillus hayakitensis DSM 18933, Lactobacillus hayakitensis DSM 18933 = JCM 14209, Lactobacillus hayakitensis JCM 14209, Lactobacillus hayakitensis JCM 14209 = DSM 18933
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