STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRM84716.1Hypothetical protein. (58 aa)    
Predicted Functional Partners:
ribA
3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family.
    
 0.773
parE
DNA topoisomerase (ATP-hydrolyzing) subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily.
   
 
 0.745
gyrB
DNA topoisomerase (ATP-hydrolyzing) subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP [...]
   
 
 0.745
KRM86089.1
Putative internalin.
    
 0.693
KRM84934.1
Hypothetical protein.
    
 0.693
guaA
Bifunctional GMP synthase glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.
    
 0.672
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
    
  0.636
KRM85899.1
Hypothetical protein.
   
 
 0.599
KRM84421.1
Hypothetical protein.
   
 
 0.596
KRM85906.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.570
Your Current Organism:
Lactobacillus hominis
NCBI taxonomy Id: 1423758
Other names: L. hominis DSM 23910 = CRBIP 24.179, Lactobacillus hominis 61D, Lactobacillus hominis CRBIP 24.179, Lactobacillus hominis CRBIP 24.179 = DSM 23910, Lactobacillus hominis DSM 23910, Lactobacillus hominis DSM 23910 = CRBIP 24.179, Lactobacillus sp. 61D
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.