STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rplE50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (180 aa)    
Predicted Functional Partners:
rpmF
Hypothetical protein; Belongs to the bacterial ribosomal protein bL32 family.
  
   0.999
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
  
 
 0.999
KRM86004.1
Hypothetical protein.
  
 0.999
rpsB
Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
 
 
 0.999
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
 
 0.999
rpsP
30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
   
 
 0.999
tuf
Translation elongation factor 1a (ef-1a ef-tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
  
 
 0.999
rpsO
Ribosomal protein S15P; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
   
 
 0.999
rpsT
30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
  
 
 0.999
rpsD
30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
 
 
 0.999
Your Current Organism:
Lactobacillus hominis
NCBI taxonomy Id: 1423758
Other names: L. hominis DSM 23910 = CRBIP 24.179, Lactobacillus hominis 61D, Lactobacillus hominis CRBIP 24.179, Lactobacillus hominis CRBIP 24.179 = DSM 23910, Lactobacillus hominis DSM 23910, Lactobacillus hominis DSM 23910 = CRBIP 24.179, Lactobacillus sp. 61D
Server load: low (22%) [HD]