STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRM85451.1Hypothetical protein. (222 aa)    
Predicted Functional Partners:
guaC
Guanosine 5-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
  
 
 0.782
KRM85450.1
Hypothetical protein.
       0.773
groS
Hypothetical protein; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
     
 0.662
KRM85448.1
Response regulator.
       0.642
KRM85449.1
Hypothetical protein.
       0.642
KRM85315.1
Cystathionine beta-synthase (CBS) domain protein.
  
 
 0.628
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.619
xpt
PTS family maltose glucose porter, IIABC component; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
  
 
 0.619
KRM84801.1
Hypoxanthine-guanine phosphoribosyltransferase like proteinue; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.591
guaA
Bifunctional GMP synthase glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.
    
 0.579
Your Current Organism:
Lactobacillus hominis
NCBI taxonomy Id: 1423758
Other names: L. hominis DSM 23910 = CRBIP 24.179, Lactobacillus hominis 61D, Lactobacillus hominis CRBIP 24.179, Lactobacillus hominis CRBIP 24.179 = DSM 23910, Lactobacillus hominis DSM 23910, Lactobacillus hominis DSM 23910 = CRBIP 24.179, Lactobacillus sp. 61D
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