STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (467 aa)    
Predicted Functional Partners:
KRL89506.1
Fumarate reductase subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.998
KRL89570.1
Fumarate reductase flavoprotein subunit.
  
 0.984
KRL88240.1
Succinate dehydrogenase.
  
 0.984
KRL88215.1
Fumarate reductase flavoprotein subunit.
  
 0.938
KRL90401.1
Succinic semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.827
KRL89449.1
Hypothetical protein.
   
 0.827
KRL89450.1
Succinate-semialdehyde dehydrogenase (NADP+).
   
 0.827
KRL89107.1
Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
   
 0.816
recA
Recombination protein A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
 
    
 0.785
KRL89571.1
Transport protein.
  
 
  0.783
Your Current Organism:
Lactobacillus kalixensis
NCBI taxonomy Id: 1423763
Other names: L. kalixensis DSM 16043, Lactobacillus kalixensis DSM 16043
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