STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRM53819.1HxlR family transcriptional regulator. (116 aa)    
Predicted Functional Partners:
KRM53818.1
Metal dependent phosphohydrolase.
  
    0.892
spoU
tRNA rRNA methyltransferase SpoU; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
       0.686
pheS
phenylalanyl-tRNA synthetase subunit alpha; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
       0.622
pheT
phenylalanyl-tRNA synthetase subunit beta; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
       0.619
KRM53816.1
Hypothetical protein.
       0.524
KRM51427.1
Cell growth regulatory protein.
   
    0.504
KRM50538.1
Transcriptional modulator of MazE toxin MazF; Toxic component of a type II toxin-antitoxin (TA) system.
   
    0.504
mltG
Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
       0.461
yidC1
YidC Oxa1 family membrane protein insertase.
       0.426
greA2
Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
  
    0.417
Your Current Organism:
Lactobacillus kefiri
NCBI taxonomy Id: 1423764
Other names: L. kefiri DSM 20587 = JCM 5818, Lactobacillus kefiri DSM 20587, Lactobacillus kefiri DSM 20587 = JCM 5818, Lactobacillus kefiri JCM 5818
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