STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRM53564.1NCS2 family nucleobase cation symporter-2. (464 aa)    
Predicted Functional Partners:
GuaD
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
    0.786
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
  
 0.768
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.670
pyrC
Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
  
 0.660
pyrF
Orotidine 5-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
  
 0.640
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.630
carB
Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family.
  
  
 0.623
carA
Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family.
  
  
 0.621
KRM52704.1
Dihydroorotate dehydrogenase family protein; Belongs to the dihydroorotate dehydrogenase family.
  
  
 0.520
KRM52705.1
Dihydroorotate dehydrogenase family protein; Belongs to the dihydroorotate dehydrogenase family.
  
  
 0.520
Your Current Organism:
Lactobacillus kefiri
NCBI taxonomy Id: 1423764
Other names: L. kefiri DSM 20587 = JCM 5818, Lactobacillus kefiri DSM 20587, Lactobacillus kefiri DSM 20587 = JCM 5818, Lactobacillus kefiri JCM 5818
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