STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRM18209.1Dihydrolipoamide dehydrogenase. (475 aa)    
Predicted Functional Partners:
KRM18208.1
Acetoin pyruvate dehydrogenase complex, E2 component, dihydrolipoamide succinyltransferase.
 0.999
KRM18207.1
Pyruvate dehydrogenase.
 0.998
KRM18206.1
Pyruvate dehydrogenase E1 component subunit alpha.
 
 0.994
KRM15417.1
Glycine cleavage system protein H.
 
  
 0.952
KRM14701.1
Thioredoxin.
  
 0.898
KRM14944.1
Nadp-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.894
KRM14081.1
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
 0.892
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.874
KRM17439.1
Glutamine synthetase.
  
 
 0.874
purQ
Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
  
 
  0.854
Your Current Organism:
Lactobacillus nantensis
NCBI taxonomy Id: 1423774
Other names: L. nantensis DSM 16982, Lactobacillus nantensis DSM 16982
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