node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KRK79098.1 | tmk | FD03_GL001461 | FD03_GL000510 | Haloacid dehalogenase family hydrolase. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.903 |
KRK79787.1 | KRK81101.1 | FD03_GL000489 | FD03_GL000693 | deoxyUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Ribonucleotide-diphosphate reductase subunit beta. | 0.421 |
KRK79787.1 | KRK81102.1 | FD03_GL000489 | FD03_GL000694 | deoxyUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.727 |
KRK79787.1 | tdk | FD03_GL000489 | FD03_GL002179 | deoxyUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Thymidine kinase. | 0.960 |
KRK79787.1 | thyA | FD03_GL000489 | FD03_GL001992 | deoxyUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.981 |
KRK79787.1 | tmk | FD03_GL000489 | FD03_GL000510 | deoxyUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.951 |
KRK79809.1 | KRK79810.1 | FD03_GL000511 | FD03_GL000512 | Aminotransferase class iv. | DNA polymerase III subunit delta. | 0.881 |
KRK79809.1 | KRK79811.1 | FD03_GL000511 | FD03_GL000513 | Aminotransferase class iv. | Hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family. | 0.855 |
KRK79809.1 | recR | FD03_GL000511 | FD03_GL000508 | Aminotransferase class iv. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.660 |
KRK79809.1 | tmk | FD03_GL000511 | FD03_GL000510 | Aminotransferase class iv. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.893 |
KRK79810.1 | KRK79809.1 | FD03_GL000512 | FD03_GL000511 | DNA polymerase III subunit delta. | Aminotransferase class iv. | 0.881 |
KRK79810.1 | KRK79811.1 | FD03_GL000512 | FD03_GL000513 | DNA polymerase III subunit delta. | Hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family. | 0.892 |
KRK79810.1 | recR | FD03_GL000512 | FD03_GL000508 | DNA polymerase III subunit delta. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.932 |
KRK79810.1 | tmk | FD03_GL000512 | FD03_GL000510 | DNA polymerase III subunit delta. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.952 |
KRK79811.1 | KRK79809.1 | FD03_GL000513 | FD03_GL000511 | Hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family. | Aminotransferase class iv. | 0.855 |
KRK79811.1 | KRK79810.1 | FD03_GL000513 | FD03_GL000512 | Hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family. | DNA polymerase III subunit delta. | 0.892 |
KRK79811.1 | recR | FD03_GL000513 | FD03_GL000508 | Hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.654 |
KRK79811.1 | tmk | FD03_GL000513 | FD03_GL000510 | Hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.896 |
KRK81101.1 | KRK79787.1 | FD03_GL000693 | FD03_GL000489 | Ribonucleotide-diphosphate reductase subunit beta. | deoxyUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 0.421 |
KRK81101.1 | KRK81102.1 | FD03_GL000693 | FD03_GL000694 | Ribonucleotide-diphosphate reductase subunit beta. | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.999 |