KRK78932.1 protein (Lactobacillus nodensis) - STRING interaction network

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Predicted Interactions

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Score

KRK78932.1

GntR family transcriptional regulator. (241 aa)

Predicted Functional Partners:

KRK80806.1

0.771

KRK78933.1

0.654

KRK78930.1

0.547

KRK78931.1

0.483

KRK80126.1

0.479

KRK79749.1

0.479

KRK78661.1

0.479

Your Current Organism:

Lactobacillus nodensis

NCBI taxonomy Id: 1423775
Other names: L. nodensis DSM 19682 = JCM 14932 = NBRC 107160, Lactobacillus nodensis DSM 19682, Lactobacillus nodensis DSM 19682 = JCM 14932 = NBRC 107160, Lactobacillus nodensis JCM 14932, Lactobacillus nodensis NBRC 107160

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KRK78661.1	KRK78932.1	FD03_GL002438	FD03_GL001291	Beta-glucosides PTS, EIIABC.	GntR family transcriptional regulator.	0.479
KRK78661.1	KRK79749.1	FD03_GL002438	FD03_GL000451	Beta-glucosides PTS, EIIABC.	N-acetylglucosamine and glucose PTS, EIICBA.	0.999
KRK78661.1	KRK80126.1	FD03_GL002438	FD03_GL000004	Beta-glucosides PTS, EIIABC.	Beta-glucosides PTS, EIIABC.	0.999
KRK78661.1	KRK80806.1	FD03_GL002438	FD03_GL000939	Beta-glucosides PTS, EIIABC.	Transcription regulator.	0.479
KRK78930.1	KRK78931.1	FD03_GL001289	FD03_GL001290	Iron-dependent peroxidase.	Choloylglycine hydrolase (bile salt hydrolase).	0.453
KRK78930.1	KRK78932.1	FD03_GL001289	FD03_GL001291	Iron-dependent peroxidase.	GntR family transcriptional regulator.	0.547
KRK78931.1	KRK78930.1	FD03_GL001290	FD03_GL001289	Choloylglycine hydrolase (bile salt hydrolase).	Iron-dependent peroxidase.	0.453
KRK78931.1	KRK78932.1	FD03_GL001290	FD03_GL001291	Choloylglycine hydrolase (bile salt hydrolase).	GntR family transcriptional regulator.	0.483
KRK78932.1	KRK78661.1	FD03_GL001291	FD03_GL002438	GntR family transcriptional regulator.	Beta-glucosides PTS, EIIABC.	0.479
KRK78932.1	KRK78930.1	FD03_GL001291	FD03_GL001289	GntR family transcriptional regulator.	Iron-dependent peroxidase.	0.547
KRK78932.1	KRK78931.1	FD03_GL001291	FD03_GL001290	GntR family transcriptional regulator.	Choloylglycine hydrolase (bile salt hydrolase).	0.483
KRK78932.1	KRK78933.1	FD03_GL001291	FD03_GL001292	GntR family transcriptional regulator.	Phosphoketolase.	0.654
KRK78932.1	KRK79749.1	FD03_GL001291	FD03_GL000451	GntR family transcriptional regulator.	N-acetylglucosamine and glucose PTS, EIICBA.	0.479
KRK78932.1	KRK80126.1	FD03_GL001291	FD03_GL000004	GntR family transcriptional regulator.	Beta-glucosides PTS, EIIABC.	0.479
KRK78932.1	KRK80806.1	FD03_GL001291	FD03_GL000939	GntR family transcriptional regulator.	Transcription regulator.	0.771
KRK78933.1	KRK78932.1	FD03_GL001292	FD03_GL001291	Phosphoketolase.	GntR family transcriptional regulator.	0.654
KRK79749.1	KRK78661.1	FD03_GL000451	FD03_GL002438	N-acetylglucosamine and glucose PTS, EIICBA.	Beta-glucosides PTS, EIIABC.	0.999
KRK79749.1	KRK78932.1	FD03_GL000451	FD03_GL001291	N-acetylglucosamine and glucose PTS, EIICBA.	GntR family transcriptional regulator.	0.479
KRK79749.1	KRK80126.1	FD03_GL000451	FD03_GL000004	N-acetylglucosamine and glucose PTS, EIICBA.	Beta-glucosides PTS, EIIABC.	0.999
KRK79749.1	KRK80806.1	FD03_GL000451	FD03_GL000939	N-acetylglucosamine and glucose PTS, EIICBA.	Transcription regulator.	0.479

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

24

average node degree:

4.36

avg. local clustering coefficient:

0.856

expected number of edges:

33

PPI enrichment p-value:

0.959

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2713

Alpha/beta hydrolase fold-1

4 of 6

2.57

3.35

1.13e-06

CL:1085

Phosphopantetheine attachment site, and Thioesterase domain

2 of 10

2.04

0.79

0.0417

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0031975

Envelope

4 of 85

1.42

1.1

0.0033

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0596

Phosphopantetheine

3 of 47

1.55

0.9

0.0158

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00561

Alpha/beta hydrolase fold

3 of 22

1.88

1.19

0.0061

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000073

Alpha/beta hydrolase fold-1

4 of 22

2.0

2.04

0.00012

IPR032821

Polyketide synthase, C-terminal extension

3 of 16

2.02

1.4

0.0028

IPR013968

Polyketide synthase, ketoreductase domain

3 of 15

2.04

1.4

0.0028

IPR016036

Malonyl-CoA ACP transacylase, ACP-binding

3 of 17

1.99

1.39

0.0028

IPR014043

Acyl transferase

3 of 17

1.99

1.39

0.0028

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00822

This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group.

3 of 13

2.11

1.88

0.00034

SM00827

Acyl transferase domain in polyketide synthase (PKS) enzymes.

3 of 15

2.04

1.85

0.00034

SM00823

Phosphopantetheine attachment site

3 of 16

2.02

1.84

0.00034

SM00826

PKS_DH

2 of 4

2.44

1.61

0.0016

SM00825

Beta-ketoacyl synthase

2 of 12

1.96

1.16

0.0078

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