STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mscLLarge-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. (121 aa)    
Predicted Functional Partners:
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
    0.733
KRL11814.1
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
     
 0.724
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
      
 0.700
KRL09815.1
Cyclopropane-fatty-acyl-phospholipid synthase.
      
 0.589
KRL09354.1
Hypothetical protein.
       0.512
KRL09293.1
Sodium hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
     
 0.494
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.494
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
       0.476
KRL09356.1
Trehalose 6-phosphate phosphorylase.
       0.468
KRL09357.1
Beta-phosphoglucomutase.
       0.441
Your Current Organism:
Lactobacillus otakiensis
NCBI taxonomy Id: 1423780
Other names: L. otakiensis DSM 19908 = JCM 15040, Lactobacillus otakiensis DSM 19908, Lactobacillus otakiensis DSM 19908 = JCM 15040, Lactobacillus otakiensis JCM 15040, Lactobacillus otakiensis JCM 15040 = DSM 19908
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