STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRL12040.13-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. (359 aa)    
Predicted Functional Partners:
KRL12004.1
Acetolactate synthase, catabolic; Belongs to the TPP enzyme family.
 0.896
KRL12135.1
Pyruvate oxidase; Belongs to the TPP enzyme family.
 0.891
KRL10470.1
Major facilitator superfamily protein.
  
 
 0.872
KRL10464.1
Hypothetical protein.
  
 
 0.871
KRL08951.1
Pyruvate oxidase; Belongs to the TPP enzyme family.
 0.867
KRL12041.1
Major facilitator superfamily permease.
 
   
 0.854
KRL09941.1
Pyruvate oxidase; Belongs to the TPP enzyme family.
 0.839
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.818
KRL08590.1
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
   
 0.796
KRL12092.1
Flavocytochrome c; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 0.739
Your Current Organism:
Lactobacillus otakiensis
NCBI taxonomy Id: 1423780
Other names: L. otakiensis DSM 19908 = JCM 15040, Lactobacillus otakiensis DSM 19908, Lactobacillus otakiensis DSM 19908 = JCM 15040, Lactobacillus otakiensis JCM 15040, Lactobacillus otakiensis JCM 15040 = DSM 19908
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.