KRK82474.1 protein (Lactobacillus paralimentarius)

Nodes:

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

KRK82474.1

Hypothetical protein. (310 aa)

Predicted Functional Partners:

KRK82476.1

0.941

KRK82470.1

0.931

KRK82471.1

0.847

KRK82463.1

0.831

KRK82473.1

0.827

KRK82472.1

0.770

KRK82477.1

0.770

KRK82454.1

0.748

KRK82475.1

0.693

KRK82469.1

0.635

Your Current Organism:

Lactobacillus paralimentarius

NCBI taxonomy Id: 1423788
Other names: L. paralimentarius DSM 19674, Lactobacillus paralimentarius DSM 19674

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KRK82454.1	KRK82463.1	FC78_GL002463	FC78_GL002472	Priming glycosyltransferase.	UDP-galactopyranose mutase.	0.581
KRK82454.1	KRK82469.1	FC78_GL002463	FC78_GL002478	Priming glycosyltransferase.	Tyrosine-protein kinase.	0.862
KRK82454.1	KRK82472.1	FC78_GL002463	FC78_GL002481	Priming glycosyltransferase.	Group 1 glycosyl transferase.	0.563
KRK82454.1	KRK82474.1	FC78_GL002463	FC78_GL002483	Priming glycosyltransferase.	Hypothetical protein.	0.748
KRK82454.1	KRK82477.1	FC78_GL002463	FC78_GL002486	Priming glycosyltransferase.	PST family polysaccharide transporter.	0.734
KRK82463.1	KRK82454.1	FC78_GL002472	FC78_GL002463	UDP-galactopyranose mutase.	Priming glycosyltransferase.	0.581
KRK82463.1	KRK82471.1	FC78_GL002472	FC78_GL002480	UDP-galactopyranose mutase.	Capsular biosynthesis protein.	0.635
KRK82463.1	KRK82472.1	FC78_GL002472	FC78_GL002481	UDP-galactopyranose mutase.	Group 1 glycosyl transferase.	0.739
KRK82463.1	KRK82474.1	FC78_GL002472	FC78_GL002483	UDP-galactopyranose mutase.	Hypothetical protein.	0.831
KRK82463.1	KRK82477.1	FC78_GL002472	FC78_GL002486	UDP-galactopyranose mutase.	PST family polysaccharide transporter.	0.762
KRK82469.1	KRK82454.1	FC78_GL002478	FC78_GL002463	Tyrosine-protein kinase.	Priming glycosyltransferase.	0.862
KRK82469.1	KRK82470.1	FC78_GL002478	FC78_GL002479	Tyrosine-protein kinase.	Galactosyltransferase.	0.941
KRK82469.1	KRK82471.1	FC78_GL002478	FC78_GL002480	Tyrosine-protein kinase.	Capsular biosynthesis protein.	0.658
KRK82469.1	KRK82472.1	FC78_GL002478	FC78_GL002481	Tyrosine-protein kinase.	Group 1 glycosyl transferase.	0.633
KRK82469.1	KRK82473.1	FC78_GL002478	FC78_GL002482	Tyrosine-protein kinase.	Glycosyl transferase family 2.	0.625
KRK82469.1	KRK82474.1	FC78_GL002478	FC78_GL002483	Tyrosine-protein kinase.	Hypothetical protein.	0.635
KRK82469.1	KRK82475.1	FC78_GL002478	FC78_GL002484	Tyrosine-protein kinase.	Hypothetical protein.	0.501
KRK82469.1	KRK82476.1	FC78_GL002478	FC78_GL002485	Tyrosine-protein kinase.	UDP-galactopyranose mutase.	0.575
KRK82469.1	KRK82477.1	FC78_GL002478	FC78_GL002486	Tyrosine-protein kinase.	PST family polysaccharide transporter.	0.470
KRK82470.1	KRK82469.1	FC78_GL002479	FC78_GL002478	Galactosyltransferase.	Tyrosine-protein kinase.	0.941

page 1 of 5

Network Stats

number of nodes:

2

number of edges:

1

average node degree:

1

avg. local clustering coefficient:

1

expected number of edges:

1

PPI enrichment p-value:

0.5

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019509

L-methionine salvage from methylthioadenosine

5 of 10

2.78

4.68

1.65e-09

GO:0019284

L-methionine salvage from S-adenosylmethionine

3 of 6

2.78

2.69

1.12e-05

GO:0044283

Small molecule biosynthetic process

6 of 545

1.12

1.03

0.00041

GO:0005996

Monosaccharide metabolic process

3 of 129

1.45

0.78

0.0220

GO:0019752

Carboxylic acid metabolic process

6 of 788

0.96

0.75

0.0026

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0043874

Acireductone synthase activity

2 of 2

3.08

1.18

0.0074

GO:0043716

2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity

2 of 2

3.08

1.18

0.0074

GO:0043715

2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity

2 of 2

3.08

1.18

0.0074

GO:0010309

Acireductone dioxygenase [iron(II)-requiring] activity

2 of 2

3.08

1.18

0.0074

GO:0010308

Acireductone dioxygenase (Ni2+-requiring) activity

2 of 2

3.08

1.18

0.0074

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:20301

Amino acid salvage, and ribitol-5-phosphatase activity

7 of 12

2.85

7.61

2.79e-15

CL:20303

L-methionine salvage from S-adenosylmethionine, and Acireductone dioxygenase ARD family

3 of 6

2.78

2.59

1.73e-05

CL:16299

Glycolytic process, and Pentose phosphate pathway

4 of 59

1.91

2.02

6.01e-05

CL:16407

Mixed, incl. Ribokinase, and Xylulose metabolic process

2 of 5

2.68

1.37

0.0032

CL:16313

Glycolytic process

2 of 19

2.1

0.86

0.0244

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00270

Cysteine and methionine metabolism

6 of 108

1.83

3.1

2.45e-08

map01100

Metabolic pathways

11 of 3633

0.56

0.49

5.09e-05

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-1237112

Methionine salvage pathway

5 of 7

2.94

5.37

1.03e-10

MAP-1614635

Sulfur amino acid metabolism

5 of 36

2.22

3.57

4.81e-08

MAP-71291

Metabolism of amino acids and derivatives

5 of 400

1.18

0.91

0.0030

MAP-71387

Metabolism of carbohydrates

4 of 333

1.16

0.67

0.0227

MAP-1430728

Metabolism

9 of 2436

0.65

0.49

0.0030

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0486

Methionine biosynthesis

3 of 8

2.66

2.57

1.75e-05

KW-0223

Dioxygenase

2 of 9

2.43

1.37

0.0029

KW-0119

Carbohydrate metabolism

2 of 17

2.15

1.16

0.0067

KW-0963

Cytoplasm

3 of 180

1.3

0.75

0.0197

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR027496

Acireductone dioxygenase, eukaryotes

2 of 2

3.08

0.96

0.0186

IPR004313

Acireductone dioxygenase ARD family

2 of 2

3.08

0.96

0.0186

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