STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRL12558.1Penicillin-binding protein precursor (Beta-lactamase class C). (590 aa)    
Predicted Functional Partners:
KRL12296.1
D-alanyl transfer protein; Could be involved in the transport of activated D-alanine through the membrane.
 
  
 0.838
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.821
dltA
D-alanine-activating enzyme; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent AMP [...]
 
  
 0.820
KRL11098.1
Beta-lactamase family protein.
  
   
 0.787
KRL13979.1
Beta-lactamase class C related penicillin binding protein.
  
     0.771
KRL12298.1
Lipoteichoic acid D-alanyl esterase precursor.
  
 0.728
KRL11354.1
Beta-lactamase class C related penicillin binding protein.
 
     0.659
KRL14446.1
Beta-glucosidase.
  
 
 0.607
KRL14485.1
Beta-glucosidase.
  
 
 0.607
KRL14730.1
Glycosyl hydrolase family 3 N terminal domain protein.
  
 
 0.607
Your Current Organism:
Lactobacillus perolens
NCBI taxonomy Id: 1423792
Other names: L. perolens DSM 12744, Lactobacillus perolens DSM 12744
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.