STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRL12408.1L-serine dehydratase, iron-sulfur-dependent subunit alpha. (289 aa)    
Predicted Functional Partners:
KRL12409.1
L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
 
 0.999
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.974
KRL13924.1
Homoserine dehydrogenase.
   
 
 0.943
trpA
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
   
 
 0.937
metAA
Homoserine trans-succinylase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
     
 0.934
KRL13771.1
Succinate-semialdehyde dehydrogenase (NADP+).
   
 
 0.908
dsdA
dsdA protein; Belongs to the serine/threonine dehydratase family. DsdA subfamily.
     
 0.882
KRL11058.1
Lactoylglutathione lyase-like protein.
   
 
  0.860
KRL12407.1
Hypothetical protein.
  
  
 0.795
KRL14300.1
Glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.714
Your Current Organism:
Lactobacillus perolens
NCBI taxonomy Id: 1423792
Other names: L. perolens DSM 12744, Lactobacillus perolens DSM 12744
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