STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRL15750.1HD domain protein. (331 aa)    
Predicted Functional Partners:
KRL15748.1
Ser Thr phosphatase family protein.
     
 0.839
KRL15749.1
Hypothetical protein.
  
    0.831
KRL15747.1
Hypothetical protein; Belongs to the UPF0342 family.
  
    0.654
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
      0.606
pbp2A
Penicillin-binding protein, 1A family.
       0.572
recU
Recombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
  
     0.505
KRL16034.1
Phosphodiesterase family protein.
  
   
 0.446
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
    0.440
KRL17021.1
Hypothetical protein; Belongs to the UPF0374 family.
  
     0.422
Your Current Organism:
Lactobacillus rapi
NCBI taxonomy Id: 1423795
Other names: L. rapi DSM 19907 = JCM 15042, Lactobacillus rapi DSM 19907, Lactobacillus rapi DSM 19907 = JCM 15042, Lactobacillus rapi JCM 15042, Lactobacillus rapi JCM 15042 = DSM 19907
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.