STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobBTranscriptional regulator, Sir2 family. (238 aa)    
Predicted Functional Partners:
gdh
Glutamate dehydrogenase (NADP(+)); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.939
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
 0.917
deoD
Purine nucleoside phosphorylase.
    
 0.912
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
    
 0.911
nadK
NAD(+) NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
   
 
 0.904
KRL17334.1
Inosine uridine-preferring nucleoside hydrolase.
   
 
  0.886
KRL16862.1
Inosine-uridine preferring nucleoside hydrolase.
   
 
  0.886
KRL17722.1
hydroxymethylglutaryl-CoA reductase, degradative; Belongs to the HMG-CoA reductase family.
  
  
 0.812
KRL18248.1
Cytidine uridine-specific hydrolase.
   
 
  0.809
KRL14988.1
Cytidine uridine-specific hydrolase.
   
 
  0.809
Your Current Organism:
Lactobacillus rapi
NCBI taxonomy Id: 1423795
Other names: L. rapi DSM 19907 = JCM 15042, Lactobacillus rapi DSM 19907, Lactobacillus rapi DSM 19907 = JCM 15042, Lactobacillus rapi JCM 15042, Lactobacillus rapi JCM 15042 = DSM 19907
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