STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rlmHrRNA large subunit methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (159 aa)    
Predicted Functional Partners:
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
  
 0.845
KRL99950.1
Methyltransferase.
 
   
 0.651
KRL98868.1
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.579
nadD
Nicotinate-nucleotide adenylyltransferase (Deamido-NAD(+) pyrophosphorylase); Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
  
 0.539
KRL98008.1
23S rRNA m(5)C methyltransferase.
 
   
 0.493
KRL99705.1
23S rRNA methyltransferase; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
  
   
 0.492
KRL99884.1
16S rRNA m(5)C 967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
     
 0.481
rsmI
Tetrapyrrole (Corrin Porphyrin) methylase family protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
 
   
 0.474
KRL98974.1
D-alanyl-d-alanine carboxypeptidase; Belongs to the peptidase S11 family.
 
  
 0.428
engB
GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
 
  
 0.420
Your Current Organism:
Lactobacillus satsumensis
NCBI taxonomy Id: 1423801
Other names: L. satsumensis DSM 16230 = JCM 12392, Lactobacillus satsumensis DSM 16230, Lactobacillus satsumensis DSM 16230 = JCM 12392, Lactobacillus satsumensis JCM 12392, Lactobacillus satsumensis JCM 12392 = DSM 16230
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