STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRM93594.1Hypothetical protein. (91 aa)    
Predicted Functional Partners:
secA
Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
   
 0.991
KRM93684.1
Preprotein translocase subunit YajC.
   
 
 0.669
KRM93483.1
Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
   
 
 0.614
KRM93415.1
Hypothetical protein; Belongs to the SecE/SEC61-gamma family.
   
 
 0.607
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
     
 0.598
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
     
 0.598
secY
Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
     
 0.598
KRM93424.1
Hypothetical protein.
  
  
 0.594
KRM93933.1
YidC Oxa1 family membrane protein insertase.
     
 0.484
KRM94329.1
Stage III sporulation protein J.
     
 0.484
Your Current Organism:
Lactobacillus senioris
NCBI taxonomy Id: 1423802
Other names: L. senioris DSM 24302 = JCM 17472, Lactobacillus senioris DSM 24302, Lactobacillus senioris DSM 24302 = JCM 17472, Lactobacillus senioris JCM 17472, Lactobacillus senioris JCM 17472 = DSM 24302, Lactobacillus senioris YIT 12364, Lactobacillus sp. YIT 12364
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