STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
KRN03049.1Phosphoenolpyruvate-protein kinase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (574 aa)    
Predicted Functional Partners:
KRN03050.1
Phosphocarrier protein HPr.
 
 0.999
KRN02571.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.927
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 
 0.652
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.637
KRN01875.1
Catabolite control protein A.
   
 
 0.631
hprK
HPr kinase phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon [...]
 
   
 0.619
KRN02837.1
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.604
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
     
 0.564
KRN02572.1
Translaldolase.
     
 0.551
KRN02839.1
Ribose operon repressor.
   
 
 0.530
Your Current Organism:
Lactobacillus senmaizukei
NCBI taxonomy Id: 1423803
Other names: L. senmaizukei DSM 21775 = NBRC 103853, Lactobacillus senmaizukei DSM 21775, Lactobacillus senmaizukei DSM 21775 = NBRC 103853, Lactobacillus senmaizukei L13, Lactobacillus senmaizukei NBRC 103853, Lactobacillus senmaizukei NBRC 103853 = DSM 21775
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