STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRN02824.1Dihydrolipoamide dehydrogenase. (475 aa)    
Predicted Functional Partners:
KRN02825.1
Acetoin pyruvate dehydrogenase complex, E2 component, dihydrolipoamide succinyltransferase.
 0.999
KRN02826.1
Acetoin dehydrogenase complex, E1 component, beta subunit.
 0.998
pdhA
Acetoin dehydrogenase complex, E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 0.991
KRN01750.1
Glycine cleavage system H protein (lipoate-binding).
 
  
 0.932
KRN03308.1
Glycine cleavage system H protein (lipoate-binding).
 
  
 0.913
KRN01606.1
Thiol-disulfide isomerase and thioredoxin.
  
 0.906
KRN01403.1
Lipoate-protein ligase A.
 
 
 0.835
KRN03309.1
Lipoate-protein ligase A.
 
 
 0.825
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.809
KRN01707.1
Glutamine synthetase.
  
 
 0.808
Your Current Organism:
Lactobacillus senmaizukei
NCBI taxonomy Id: 1423803
Other names: L. senmaizukei DSM 21775 = NBRC 103853, Lactobacillus senmaizukei DSM 21775, Lactobacillus senmaizukei DSM 21775 = NBRC 103853, Lactobacillus senmaizukei L13, Lactobacillus senmaizukei NBRC 103853, Lactobacillus senmaizukei NBRC 103853 = DSM 21775
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