STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRN21179.1Integral membrane protein. (315 aa)    
Predicted Functional Partners:
KRN21180.1
Oxidoreductase.
       0.742
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.596
pyrF
Orotidine-5-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
    0.590
KRN23910.1
Hypothetical protein; Catalyzes the conversion of dihydroorotate to orotate.
  
    0.586
KRN21178.1
Hypothetical protein.
 
     0.551
pyrC
Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
    0.473
KRN23908.1
NCS family uracil cation symporter.
   
  
 0.455
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
   
    0.441
Your Current Organism:
Lactobacillus similis
NCBI taxonomy Id: 1423804
Other names: L. similis DSM 23365 = JCM 2765, Lactobacillus similis DSM 23365, Lactobacillus similis DSM 23365 = JCM 2765, Lactobacillus similis JCM 2765, Lactobacillus similis JCM 2765 = DSM 23365, Lactobacillus sp. JCM 2765
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