STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnjmRNA degradation ribonuclease J1 J2enzyme; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (558 aa)    
Predicted Functional Partners:
rnj-2
Metallo-beta-lactamase superfamily hydrolase; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
  
  
 
0.893
KRN26345.1
Hypothetical protein; Belongs to the UPF0356 family.
  
    0.892
rny
Phosphodiesterase; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.
  
 
 0.678
rny-2
HD superfamily hydrolase; Endoribonuclease that initiates mRNA decay.
  
 
 0.678
KRN26343.1
Diacylglycerol kinase family protein.
  
    0.608
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
  
 0.582
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
 
    0.581
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
  
 0.577
metG
methionine-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
 
    0.575
KRN19920.1
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
    0.550
Your Current Organism:
Lactobacillus similis
NCBI taxonomy Id: 1423804
Other names: L. similis DSM 23365 = JCM 2765, Lactobacillus similis DSM 23365, Lactobacillus similis DSM 23365 = JCM 2765, Lactobacillus similis JCM 2765, Lactobacillus similis JCM 2765 = DSM 23365, Lactobacillus sp. JCM 2765
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