STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRM11551.1DNA protecting protein DprA. (269 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.908
KRM12511.1
ComE operon protein 3.
 
  
 0.794
KRM13605.1
Amidophosphoribosyltransferase-like protein.
 
 
 0.757
KRM13378.1
Bacterial peptidase A24 domain-containing protein.
  
  
 0.722
KRM11549.1
GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
  
    0.691
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
    0.690
KRM11548.1
Hypothetical protein; Belongs to the UPF0346 family.
       0.663
KRM12642.1
Single-strand DNA binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
 
  
 0.659
pyrB
Aspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
      0.649
KRM12494.1
single-stranded-DNA-specific exonuclease RecJ.
 
   
 0.649
Your Current Organism:
Lactobacillus suebicus
NCBI taxonomy Id: 1423807
Other names: L. suebicus DSM 5007 = KCTC 3549, Lactobacillus suebicus DSM 5007, Lactobacillus suebicus DSM 5007 = KCTC 3549, Lactobacillus suebicus KCTC 3549, Lactobacillus suebicus KCTC 3549 = DSM 5007
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.