STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaXDNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (584 aa)    
Predicted Functional Partners:
KRM12648.1
DNA-directed DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for i [...]
 
 
 0.994
KRM12099.1
DNA polymerase III catalytic subunit, DnaE type.
 
 0.993
KRM12510.1
DNA polymerase III, delta subunit.
   
 0.993
KRM13565.1
DNA polymerase III, epsilon subunit related 3-5 exonuclease.
   
 0.978
KRM11010.1
DNA polymerase III subunit delta.
 
  
 
0.971
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
  
 0.953
dinG
DnaQ family exonuclease DinG family helicase; 3'-5' exonuclease.
 
 0.931
polC
DNA polymerase III PolC; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.926
KRM12642.1
Single-strand DNA binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
   
 
 0.907
KRM11005.1
Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
  
  
 0.897
Your Current Organism:
Lactobacillus suebicus
NCBI taxonomy Id: 1423807
Other names: L. suebicus DSM 5007 = KCTC 3549, Lactobacillus suebicus DSM 5007, Lactobacillus suebicus DSM 5007 = KCTC 3549, Lactobacillus suebicus KCTC 3549, Lactobacillus suebicus KCTC 3549 = DSM 5007
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.